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Research Area
홈
Research Area
Therapeutics & Biotechnology
Data Convergence Drug Research Center

Data Convergence Drug Research Center

Data Convergence Drug Research Center
Head
  • NameSunjoo Ahn
  • Office+82-42-860-7170
  • Mailsahn@krict.re.kr
Sunjoo Ahn

Major research fields

Research on new drug pipeline based on convergence of multi-omics big data

  • New target discovery for intractable diseases based on patient genomic data
  • Drug-transcriptome data based chemical discovery for treatment
  • Research on intractable disease candidate mechanisms based on next-generation sequencing data
  • Companion diagnostic biomarkers for innovative new drugs in precision medicine

AI-powered activity, toxicity, and drugability prediction algorithms

  • Toxicity, drugability prediction and deep neural network algorithms based on compound structure
  • Development of test methods for experimental verification and algorithm optimization using the method
  • Establishment of drug rescue platform to improve toxicity and drugability of drug candidates of which development has been suspended

Proteolytic technology-based new drug pipeline research

  • Discovery of novel E3 ligase binders and innovative targeted PROTAC (PROteolysis TArgeting Chimera)
  • Establishment of a unique and diverse molecular glue library and discovery of molecular glue degrader
  • Immune cell activity control using proteolytic agents
  • Establishment of DNA-encoded library (DEL) for PROTAC use